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Metabolomic Profiling of the Effects of Melittin on Cisplatin Resistant and Cisplatin Sensitive Ovarian Cancer Cells Using Mass Spectrometry and Biolog Microarray Technology
In the present study, liquid chromatography-mass spectrometry (LC-MS) was employed to characterise the metabolic profiles of two human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780CR (cisplatin-resistant) in response to their exposure to melittin, a cytotoxic peptide from bee venom...
Autores principales: | Alonezi, Sanad, Tusiimire, Jonans, Wallace, Jennifer, Dufton, Mark J., Parkinson, John A., Young, Louise C., Clements, Carol J., Park, Jin Kyu, Jeon, Jong Woon, Ferro, Valerie A., Watson, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192441/ https://www.ncbi.nlm.nih.gov/pubmed/27754384 http://dx.doi.org/10.3390/metabo6040035 |
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