Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

New thiazole nortopsentin analogs in which one of the two indole units was replaced by a naphthyl and/or 7-azaindolyl portion, were conveniently synthesized. Among these, three derivatives showed good antiproliferative activity, in particular against MCF7 cell line, with GI(50) values in the micromo...

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Detalles Bibliográficos
Autores principales: Spanò, Virginia, Attanzio, Alessandro, Cascioferro, Stella, Carbone, Anna, Montalbano, Alessandra, Barraja, Paola, Tesoriere, Luisa, Cirrincione, Girolamo, Diana, Patrizia, Parrino, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192463/
https://www.ncbi.nlm.nih.gov/pubmed/27983614
http://dx.doi.org/10.3390/md14120226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192463/
https://www.ncbi.nlm.nih.gov/pubmed/27983614
http://dx.doi.org/10.3390/md14120226

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