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First Total Synthesis and Biological Screening of a Proline-Rich Cyclopeptide from a Caribbean Marine Sponge

A natural heptacyclopeptide, stylissamide G (7), previously isolated from the Bahamian marine sponge Stylissa caribica from the Caribbean Sea, was synthesized via coupling of the tetrapeptide l-phenylalanyl-l-prolyl-l-phenylalanyl-l-proline methyl ester with the tripeptide Boc-l-leucyl-l-isoleucyl-l...

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Detalles Bibliográficos
Autores principales: Dahiya, Rajiv, Singh, Sunil, Sharma, Ajay, Chennupati, Suresh V., Maharaj, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192465/
https://www.ncbi.nlm.nih.gov/pubmed/27983681
http://dx.doi.org/10.3390/md14120228