Alginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis

Doxorubicin (DOX) is a highly potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. DOX-induced cardiotoxicity involves increased oxidative stress and activated endoplasmic reticulum-mediated apoptosis. Alginate oligosaccharide (AOS) is a non-immunogenic, non-toxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Jun-Jie, Ma, Lei-Lei, Shi, Hong-Tao, Zhu, Jian-Bing, Wu, Jian, Ding, Zhi-Wen, An, Yi, Zou, Yun-Zeng, Ge, Jun-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192468/
https://www.ncbi.nlm.nih.gov/pubmed/27999379
http://dx.doi.org/10.3390/md14120231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192468/
https://www.ncbi.nlm.nih.gov/pubmed/27999379
http://dx.doi.org/10.3390/md14120231

Ejemplares similares