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Alginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis

Doxorubicin (DOX) is a highly potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. DOX-induced cardiotoxicity involves increased oxidative stress and activated endoplasmic reticulum-mediated apoptosis. Alginate oligosaccharide (AOS) is a non-immunogenic, non-toxi...

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Detalles Bibliográficos
Autores principales:	Guo, Jun-Jie, Ma, Lei-Lei, Shi, Hong-Tao, Zhu, Jian-Bing, Wu, Jian, Ding, Zhi-Wen, An, Yi, Zou, Yun-Zeng, Ge, Jun-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192468/ https://www.ncbi.nlm.nih.gov/pubmed/27999379 http://dx.doi.org/10.3390/md14120231

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