Postnatal Gene Therapy Improves Spatial Learning Despite the Presence of Neuronal Ectopia in a Model of Neuronal Migration Disorder

Patients with type II lissencephaly, a neuronal migration disorder with ectopic neurons, suffer from severe mental retardation, including learning deficits. There is no effective therapy to prevent or correct the formation of neuronal ectopia, which is presumed to cause cognitive deficits. We hypoth...

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Detalles Bibliográficos
Autores principales: Hu, Huaiyu, Liu, Yu, Bampoe, Kevin, He, Yonglin, Yu, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192481/
https://www.ncbi.nlm.nih.gov/pubmed/27916859
http://dx.doi.org/10.3390/genes7120105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192481/
https://www.ncbi.nlm.nih.gov/pubmed/27916859
http://dx.doi.org/10.3390/genes7120105

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