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Evaluation of Methylation Biomarkers for Detection of Circulating Tumor DNA and Application to Colorectal Cancer

Solid tumors shed DNA into circulation, and there is growing evidence that the detection of circulating tumor DNA (ctDNA) has broad clinical utility, including monitoring of disease, prognosis, response to chemotherapy and tracking tumor heterogeneity. The appearance of ctDNA in the circulating cell...

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Detalles Bibliográficos
Autores principales: Mitchell, Susan M., Ho, Thu, Brown, Glenn S., Baker, Rohan T., Thomas, Melissa L., McEvoy, Aidan, Xu, Zheng-Zhou, Ross, Jason P., Lockett, Trevor J., Young, Graeme P., LaPointe, Lawrence C., Pedersen, Susanne K., Molloy, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192501/
https://www.ncbi.nlm.nih.gov/pubmed/27983717
http://dx.doi.org/10.3390/genes7120125