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The Causes and Consequences of Topological Stress during DNA Replication

The faithful replication of sister chromatids is essential for genomic integrity in every cell division. The replication machinery must overcome numerous difficulties in every round of replication, including DNA topological stress. Topological stress arises due to the double-stranded helical nature...

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Detalles Bibliográficos
Autores principales: Keszthelyi, Andrea, Minchell, Nicola E., Baxter, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192510/
https://www.ncbi.nlm.nih.gov/pubmed/28009828
http://dx.doi.org/10.3390/genes7120134