Cargando…

The Causes and Consequences of Topological Stress during DNA Replication

The faithful replication of sister chromatids is essential for genomic integrity in every cell division. The replication machinery must overcome numerous difficulties in every round of replication, including DNA topological stress. Topological stress arises due to the double-stranded helical nature...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keszthelyi, Andrea, Minchell, Nicola E., Baxter, Jonathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192510/ https://www.ncbi.nlm.nih.gov/pubmed/28009828 http://dx.doi.org/10.3390/genes7120134

Ejemplares similares

Cohesin Causes Replicative DNA Damage by Trapping DNA Topological Stress
por: Minchell, Nicola Elizabeth, et al.
Publicado: (2020)

Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress
por: Westhorpe, Rose, et al.
Publicado: (2020)

Checkpoint inhibition of origin firing prevents DNA topological stress
por: Morafraile, Esther C., et al.
Publicado: (2019)

E2F1: Cause and Consequence of DNA Replication Stress
por: Fouad, Shahd, et al.
Publicado: (2021)

Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing
por: Billard, Pauline, et al.
Publicado: (2019)

Replication Stress in Mammalian Cells and Its Consequences for Mitosis
por: Gelot, Camille, et al.
Publicado: (2015)

Histone dynamics during DNA replication stress
por: Hsu, Chia-Ling, et al.
Publicado: (2021)

Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response
por: Graziano, Simona, et al.
Publicado: (2018)

Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress
por: Tsao, Wei-Chung, et al.
Publicado: (2018)

The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress
por: Lebdy, Rana, et al.
Publicado: (2023)

Causes, consequences and biomarkers of stress in swine: an update
por: Martínez-Miró, Silvia, et al.
Publicado: (2016)

Oxidative Stress in Kidney Diseases: The Cause or the Consequence?
por: Krata, Natalia, et al.
Publicado: (2017)

The Role of the Transcriptional Response to DNA Replication Stress
por: Herlihy, Anna E., et al.
Publicado: (2017)

Managing Single-Stranded DNA during Replication Stress in Fission Yeast
por: Sabatinos, Sarah A., et al.
Publicado: (2015)

Consequences and Resolution of Transcription–Replication Conflicts
por: Lalonde, Maxime, et al.
Publicado: (2021)

Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription
por: Pai, Chen-Chun, et al.
Publicado: (2017)

RTEL1 and MCM10 overcome topological stress during vertebrate replication termination
por: Campos, Lillian V., et al.
Publicado: (2023)

Microglial Responses to Stress-Induced Depression: Causes and Consequences
por: Afridi, Ruqayya, et al.
Publicado: (2023)

DNA replication stress and cancer chemotherapy
por: Kitao, Hiroyuki, et al.
Publicado: (2017)

DNA METHYLATION: CAUSE OR CONSEQUENCE OF AGING?
por: Levine, Morgan E, et al.
Publicado: (2019)

Targeting DNA Replication Stress for Cancer Therapy
por: Zhang, Jun, et al.
Publicado: (2016)

Therapeutic Targeting of DNA Replication Stress in Cancer
por: Gu, Long, et al.
Publicado: (2023)

Pathways for maintenance of telomeres and common fragile sites during DNA replication stress
por: Özer, Özgün, et al.
Publicado: (2018)

DNA methylation: a cause and consequence of type 2 diabetes
por: Kim, Mirang
Publicado: (2019)

Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA
por: Iyer, Divya Ramalingam, et al.
Publicado: (2017)

Oxidative Stress in the Pathogenesis of Colorectal Cancer: Cause or Consequence?
por: Perše, Martina
Publicado: (2013)

Cellular Stress in the Pathogenesis of Muscular Disorders—From Cause to Consequence
por: Mensch, Alexander, et al.
Publicado: (2020)

Stressed DNA replication generates stressed DNA
por: Klein, Hannah L.
Publicado: (2020)

Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts
por: Lang, Kevin S., et al.
Publicado: (2021)

3D Genome Organization: Causes and Consequences for DNA Damage and Repair
por: Carré-Simon, Ànnia, et al.
Publicado: (2021)

Harnessing DNA Replication Stress for Novel Cancer Therapy
por: Zhu, Huanbo, et al.
Publicado: (2020)

DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons
por: Wilhelm, Therese, et al.
Publicado: (2020)

The Caulobacter crescentus DciA promotes chromosome replication through topological loading of the DnaB replicative helicase at replication forks
por: Ozaki, Shogo, et al.
Publicado: (2022)

Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites
por: Basbous, Jihane, et al.
Publicado: (2020)

Physiological Responses Manifested by Some Conventional Stress Parameters and Biophoton Emission in Winter Wheat as a Consequence of Cereal Leaf Beetle Infestation
por: Lukács, Helga, et al.
Publicado: (2022)

DNA-Topology Simplification by Topoisomerases
por: Hanke, Andreas, et al.
Publicado: (2021)

Controlling the topology of mammalian mitochondrial DNA
por: Menger, Katja E., et al.
Publicado: (2021)

Oxidative Stress and Metabolic Syndrome: Cause or Consequence of Alzheimer's Disease?
por: Luque-Contreras, Diana, et al.
Publicado: (2014)

Is oxidative stress of adipocytes a cause or a consequence of the metabolic syndrome?
por: Maslov, Leonid N., et al.
Publicado: (2018)

The Mutagenic Consequences of DNA Methylation within and across Generations
por: Hanson, Haley E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sb5f7vlqroo9m9tpsd54n3kjt4