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The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes

BACKGROUND: The dynamic three-dimensional chromatin architecture of genomes and its co-evolutionary connection to its function—the storage, expression, and replication of genetic information—is still one of the central issues in biology. Here, we describe the much debated 3D architecture of the huma...

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Detalles Bibliográficos
Autores principales: Knoch, Tobias A., Wachsmuth, Malte, Kepper, Nick, Lesnussa, Michael, Abuseiris, Anis, Ali Imam, A. M., Kolovos, Petros, Zuin, Jessica, Kockx, Christel E. M., Brouwer, Rutger W. W., van de Werken, Harmen J. G., van IJcken, Wilfred F. J., Wendt, Kerstin S., Grosveld, Frank G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192698/
https://www.ncbi.nlm.nih.gov/pubmed/28035242
http://dx.doi.org/10.1186/s13072-016-0089-x