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Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells

In central nervous system, glioma is the most common primary brain tumour. The diffuse migration and rapid proliferation are main obstacles for successful treatment. Gartanin, a natural xanthone of mangosteen, suppressed proliferation, migration and colony formation in a time‐ and concentration‐depe...

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Detalles Bibliográficos
Autores principales: Luo, Ming, Liu, Qingyu, He, Mingliang, Yu, Zhiling, Pi, Rongbiao, Li, Min, Yang, Xiaohong, Wang, Shengnan, Liu, Anmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192955/
https://www.ncbi.nlm.nih.gov/pubmed/27491646
http://dx.doi.org/10.1111/jcmm.12937