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Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells
In central nervous system, glioma is the most common primary brain tumour. The diffuse migration and rapid proliferation are main obstacles for successful treatment. Gartanin, a natural xanthone of mangosteen, suppressed proliferation, migration and colony formation in a time‐ and concentration‐depe...
Autores principales: | Luo, Ming, Liu, Qingyu, He, Mingliang, Yu, Zhiling, Pi, Rongbiao, Li, Min, Yang, Xiaohong, Wang, Shengnan, Liu, Anmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192955/ https://www.ncbi.nlm.nih.gov/pubmed/27491646 http://dx.doi.org/10.1111/jcmm.12937 |
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