Population Pharmacokinetics of Bedaquiline and Metabolite M2 in Patients With Drug‐Resistant Tuberculosis: The Effect of Time‐Varying Weight and Albumin

Albumin concentration and body weight are altered in patients with multidrug‐resistant tuberculosis (MDR‐TB) and change during the long treatment period, potentially affecting drug disposition. We here describe the pharmacokinetics (PKs) of the novel anti‐TB drug bedaquiline and its metabolite M2 in...

Descripción completa

Detalles Bibliográficos
Autores principales: Svensson, EM, Dosne, A‐G, Karlsson, MO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192973/
https://www.ncbi.nlm.nih.gov/pubmed/27863179
http://dx.doi.org/10.1002/psp4.12147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192973/
https://www.ncbi.nlm.nih.gov/pubmed/27863179
http://dx.doi.org/10.1002/psp4.12147

Ejemplares similares