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Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo‐electron microscopy

The tremendous pandemic potential of coronaviruses was demonstrated twice in the last 15 years by two global outbreaks of deadly pneumonia. Entry of coronaviruses into cells is mediated by the transmembrane spike glycoprotein S, which forms a trimer carrying receptor‐binding and membrane fusion func...

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Detalles Bibliográficos
Autores principales: Walls, Alexandra, Tortorici, M. Alejandra, Bosch, Berend‐Jan, Frenz, Brandon, Rottier, Peter J. M., DiMaio, Frank, Rey, Felix A., Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192993/
https://www.ncbi.nlm.nih.gov/pubmed/27667334
http://dx.doi.org/10.1002/pro.3048