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Integrating Clinical Phenotype and Gene Expression Data to Prioritize Novel Drug Uses
Drug repositioning has been based largely on genomic signatures of drugs and diseases. One challenge in these efforts lies in connecting the molecular signatures of drugs into clinical responses, including therapeutic and side effects, to the repurpose of drugs. We addressed this challenge by evalua...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192994/ https://www.ncbi.nlm.nih.gov/pubmed/27860440 http://dx.doi.org/10.1002/psp4.12108 |