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A Mathematical Modeling Approach to Understanding the Effect of Anti‐Interleukin Therapy on Eosinophils

Emerging T‐helper type 2 (Th(2)) cytokine‐based asthma therapies, such as tralokinumab, lebrikizumab (anti‐interleukin (IL)‐13), and mepolizumab (anti‐IL‐5), have shown differences in their blood eosinophil (EOS) response. To better understand these effects, we developed a mathematical model of EOS...

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Detalles Bibliográficos
Autores principales: Karelina, T, Voronova, V, Demin, O, Colice, G, Agoram, BM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192997/
https://www.ncbi.nlm.nih.gov/pubmed/27885827
http://dx.doi.org/10.1002/psp4.12129