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A Mathematical Modeling Approach to Understanding the Effect of Anti‐Interleukin Therapy on Eosinophils
Emerging T‐helper type 2 (Th(2)) cytokine‐based asthma therapies, such as tralokinumab, lebrikizumab (anti‐interleukin (IL)‐13), and mepolizumab (anti‐IL‐5), have shown differences in their blood eosinophil (EOS) response. To better understand these effects, we developed a mathematical model of EOS...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192997/ https://www.ncbi.nlm.nih.gov/pubmed/27885827 http://dx.doi.org/10.1002/psp4.12129 |