Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed‐Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats

The objective of this study was to model the pharmacokinetics (PKs) of robenacoxib in cats using a nonlinear mixed‐effects (NLME) approach, leveraging all available information collected from cats receiving robenacoxib s.c. and/or i.v.: 47 densely sampled laboratory cats and 36 clinical cats sparsel...

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Detalles Bibliográficos
Autores principales: Pelligand, L, Soubret, A, King, JN, Elliott, J, Mochel, JP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193001/
https://www.ncbi.nlm.nih.gov/pubmed/27770596
http://dx.doi.org/10.1002/psp4.12141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193001/
https://www.ncbi.nlm.nih.gov/pubmed/27770596
http://dx.doi.org/10.1002/psp4.12141

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