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High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells
Essential characteristics of cellular signaling networks include a complex interconnected architecture and temporal dynamics of protein activity. The latter can be monitored by Förster resonance energy transfer (FRET) biosensors at a single-live-cell level with high temporal resolution. However, the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193178/ https://www.ncbi.nlm.nih.gov/pubmed/27939899 http://dx.doi.org/10.1016/j.chembiol.2016.11.008 |