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High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells

Essential characteristics of cellular signaling networks include a complex interconnected architecture and temporal dynamics of protein activity. The latter can be monitored by Förster resonance energy transfer (FRET) biosensors at a single-live-cell level with high temporal resolution. However, the...

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Detalles Bibliográficos
Autores principales:	Kuchenov, Dmitry, Laketa, Vibor, Stein, Frank, Salopiata, Florian, Klingmüller, Ursula, Schultz, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193178/ https://www.ncbi.nlm.nih.gov/pubmed/27939899 http://dx.doi.org/10.1016/j.chembiol.2016.11.008

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