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DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms
The transforming growth factor-beta 1 (TGFβ1) promotes fibrosis, differentiating epithelial cells and quiescent fibroblasts into myofibroblasts and increasing expression of extracellular matrix. Recent investigations have shown that PPAR (peroxisome proliferator-activated receptor*) is a negative re...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Sociedade Brasileira de Dermatologia
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193189/ https://www.ncbi.nlm.nih.gov/pubmed/28099600 http://dx.doi.org/10.1590/abd1806-4841.20165029 |