Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to Lysosomes

Parkinson’s disease and other alpha-synucleinopathies are progressive neurodegenerative diseases characterized by aggregates of misfolded alpha-synuclein spreading throughout the brain. Recent evidence suggests that the pathological progression is likely due to neuron-to-neuron transfer of these agg...

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Detalles Bibliográficos
Autores principales: Domert, Jakob, Sackmann, Christopher, Severinsson, Emelie, Agholme, Lotta, Bergström, Joakim, Ingelsson, Martin, Hallbeck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193351/
https://www.ncbi.nlm.nih.gov/pubmed/28030591
http://dx.doi.org/10.1371/journal.pone.0168700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193351/
https://www.ncbi.nlm.nih.gov/pubmed/28030591
http://dx.doi.org/10.1371/journal.pone.0168700

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