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CD5-CK2 Signaling Modulates Erk Activation and Thymocyte Survival
CD5 is well recognized for its importance in thymic selection. Although this property of CD5 has been attributed to its ITIM-domain dependent regulation of TCR-signal strength, the mechanism has not been established. A second major signaling domain within the cytoplasmic tail of CD5 is a CK2 binding...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193405/ https://www.ncbi.nlm.nih.gov/pubmed/28030587 http://dx.doi.org/10.1371/journal.pone.0168155 |