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CD5-CK2 Signaling Modulates Erk Activation and Thymocyte Survival

CD5 is well recognized for its importance in thymic selection. Although this property of CD5 has been attributed to its ITIM-domain dependent regulation of TCR-signal strength, the mechanism has not been established. A second major signaling domain within the cytoplasmic tail of CD5 is a CK2 binding...

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Detalles Bibliográficos
Autores principales:	Mier-Aguilar, Carlos A., Cashman, Kevin S., Raman, Chander, Soldevila, Gloria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193405/ https://www.ncbi.nlm.nih.gov/pubmed/28030587 http://dx.doi.org/10.1371/journal.pone.0168155

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