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Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase

The Gram negative bacteria Chlamydia trachomatis is an obligate intracellular human pathogen that can cause pelvic inflammatory disease, infertility and blinding trachoma. C. trachomatis encodes a homolog of the dithiol oxidoreductase DsbA. Bacterial DsbA proteins introduce disulfide bonds to foldin...

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Detalles Bibliográficos
Autores principales: Christensen, Signe, Grøftehauge, Morten K., Byriel, Karl, Huston, Wilhelmina M., Furlong, Emily, Heras, Begoña, Martin, Jennifer L., McMahon, Róisín M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193440/
https://www.ncbi.nlm.nih.gov/pubmed/28030602
http://dx.doi.org/10.1371/journal.pone.0168485