Cargando…

Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening

To date, lentiviral-based CRISPR-Cas9 screens have largely been conducted in pooled format. However, numerous assays are not amenable to pooled approaches, and lentiviral screening in arrayed format presents many challenges. We sought to examine synthetic CRISPR reagents in the context of arrayed sc...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Jenille, Martin, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193459/
https://www.ncbi.nlm.nih.gov/pubmed/28030641
http://dx.doi.org/10.1371/journal.pone.0168968