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Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening
To date, lentiviral-based CRISPR-Cas9 screens have largely been conducted in pooled format. However, numerous assays are not amenable to pooled approaches, and lentiviral screening in arrayed format presents many challenges. We sought to examine synthetic CRISPR reagents in the context of arrayed sc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193459/ https://www.ncbi.nlm.nih.gov/pubmed/28030641 http://dx.doi.org/10.1371/journal.pone.0168968 |