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The Heterogeneity of Ly6C(hi) Monocytes Controls Their Differentiation into iNOS(+) Macrophages or Monocyte-Derived Dendritic Cells

Inflammation triggers the differentiation of Ly6C(hi) monocytes into microbicidal macrophages or monocyte-derived dendritic cells (moDCs). Yet, it is unclear whether environmental inflammatory cues control the polarization of monocytes toward each of these fates or whether specialized monocyte proge...

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Detalles Bibliográficos
Autores principales: Menezes, Shinelle, Melandri, Daisy, Anselmi, Giorgio, Perchet, Thibaut, Loschko, Jakob, Dubrot, Juan, Patel, Rajen, Gautier, Emmanuel L., Hugues, Stéphanie, Longhi, M. Paula, Henry, Jake Y., Quezada, Sergio A., Lauvau, Grégoire, Lennon-Duménil, Ana-Maria, Gutiérrez-Martínez, Enrique, Bessis, Alain, Gomez-Perdiguero, Elisa, Jacome-Galarza, Christian E., Garner, Hannah, Geissmann, Frederic, Golub, Rachel, Nussenzweig, Michel C., Guermonprez, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196026/
https://www.ncbi.nlm.nih.gov/pubmed/28002729
http://dx.doi.org/10.1016/j.immuni.2016.12.001