The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

Mitochondria play a crucial role in tubular injury in diabetic kidney disease (DKD). MitoQ is a mitochondria-targeted antioxidant that exerts protective effects in diabetic mice, but the mechanism underlying these effects is not clear. We demonstrated that mitochondrial abnormalities, such as defect...

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Detalles Bibliográficos
Autores principales: Xiao, Li, Xu, Xiaoxuan, Zhang, Fan, Wang, Ming, Xu, Yan, Tang, Dan, Wang, Jiahui, Qin, Yan, Liu, Yu, Tang, Chengyuan, He, Liyu, Greka, Anna, Zhou, Zhiguang, Liu, Fuyou, Dong, Zheng, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196243/
https://www.ncbi.nlm.nih.gov/pubmed/28033563
http://dx.doi.org/10.1016/j.redox.2016.12.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196243/
https://www.ncbi.nlm.nih.gov/pubmed/28033563
http://dx.doi.org/10.1016/j.redox.2016.12.022

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