The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

Mitochondria play a crucial role in tubular injury in diabetic kidney disease (DKD). MitoQ is a mitochondria-targeted antioxidant that exerts protective effects in diabetic mice, but the mechanism underlying these effects is not clear. We demonstrated that mitochondrial abnormalities, such as defect...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Li, Xu, Xiaoxuan, Zhang, Fan, Wang, Ming, Xu, Yan, Tang, Dan, Wang, Jiahui, Qin, Yan, Liu, Yu, Tang, Chengyuan, He, Liyu, Greka, Anna, Zhou, Zhiguang, Liu, Fuyou, Dong, Zheng, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196243/
https://www.ncbi.nlm.nih.gov/pubmed/28033563
http://dx.doi.org/10.1016/j.redox.2016.12.022

Ejemplares similares

Ejemplares similares