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Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

A proximity effect has been invoked to explain the enhanced activity of enzyme cascades on DNA scaffolds. Using the cascade reaction carried out by glucose oxidase and horseradish peroxidase as a model system, here we study the kinetics of the cascade reaction when the enzymes are free in solution,...

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Detalles Bibliográficos
Autores principales: Zhang, Yifei, Tsitkov, Stanislav, Hess, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196434/
https://www.ncbi.nlm.nih.gov/pubmed/28004753
http://dx.doi.org/10.1038/ncomms13982