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Polymorphism in ion channel genes of Dirofilaria immitis: Relevant knowledge for future anthelmintic drug design

Dirofilaria immitis, a filarial parasite, causes cardiopulmonary dirofilariasis in dogs, cats and wild canids. The macrocyclic lactone (ML) class of drugs has been used to prevent heartworm infection. There is confirmed ML resistance in D. immitis and thus there is an urgent need to find new anthelm...

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Detalles Bibliográficos
Autores principales: Mani, Thangadurai, Bourguinat, Catherine, Keller, Kathy, Carreton, Elena, Peregrine, Andrew, Prichard, Roger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196487/
https://www.ncbi.nlm.nih.gov/pubmed/27682347
http://dx.doi.org/10.1016/j.ijpddr.2016.06.003