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Polymorphism in ion channel genes of Dirofilaria immitis: Relevant knowledge for future anthelmintic drug design
Dirofilaria immitis, a filarial parasite, causes cardiopulmonary dirofilariasis in dogs, cats and wild canids. The macrocyclic lactone (ML) class of drugs has been used to prevent heartworm infection. There is confirmed ML resistance in D. immitis and thus there is an urgent need to find new anthelm...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196487/ https://www.ncbi.nlm.nih.gov/pubmed/27682347 http://dx.doi.org/10.1016/j.ijpddr.2016.06.003 |