In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1

Macrocyclic lactones (ML) are important anthelmintics used in animals and humans against parasite nematodes, but their therapeutic success is compromised by the spread of ML resistance. Some ABC transporters, such as p-glycoproteins (Pgps), are selected and overexpressed in ML-resistant nematodes, s...

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Detalles Bibliográficos
Autores principales: David, Marion A., Orlowski, Stéphane, Prichard, Roger K., Hashem, Shaima, André, François, Lespine, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Invited Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196494/
https://www.ncbi.nlm.nih.gov/pubmed/27746191
http://dx.doi.org/10.1016/j.ijpddr.2016.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196494/
https://www.ncbi.nlm.nih.gov/pubmed/27746191
http://dx.doi.org/10.1016/j.ijpddr.2016.09.001

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