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In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1
Macrocyclic lactones (ML) are important anthelmintics used in animals and humans against parasite nematodes, but their therapeutic success is compromised by the spread of ML resistance. Some ABC transporters, such as p-glycoproteins (Pgps), are selected and overexpressed in ML-resistant nematodes, s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196494/ https://www.ncbi.nlm.nih.gov/pubmed/27746191 http://dx.doi.org/10.1016/j.ijpddr.2016.09.001 |