Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model

OBJECTIVES: Osteoarthritis (OA) is the most common joint disease throughout the world. Exosomes derived from miR-140-5p-overexpressing synovial mesenchymal stem cells (SMSC-140s) may be effective in treating OA. We hypothesized that exosomes derived from SMSC-140 (SMSC-140-Exos) would enhance the pr...

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Detalles Bibliográficos
Autores principales: Tao, Shi-Cong, Yuan, Ting, Zhang, Yue-Lei, Yin, Wen-Jing, Guo, Shang-Chun, Zhang, Chang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196895/
https://www.ncbi.nlm.nih.gov/pubmed/28042326
http://dx.doi.org/10.7150/thno.17133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196895/
https://www.ncbi.nlm.nih.gov/pubmed/28042326
http://dx.doi.org/10.7150/thno.17133

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