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Enhancing Nanoparticle Accumulation and Retention in Desmoplastic Tumors via Vascular Disruption for Internal Radiation Therapy

Aggressive, desmoplastic tumors are notoriously difficult to treat because of their extensive stroma, high interstitial pressure, and resistant tumor microenvironment. We have developed a combination therapy that can significantly slow the growth of large, stroma-rich tumors by causing massive apopt...

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Detalles Bibliográficos
Autores principales: Satterlee, Andrew B., Rojas, Juan D., Dayton, Paul A., Huang, Leaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197062/
https://www.ncbi.nlm.nih.gov/pubmed/28042332
http://dx.doi.org/10.7150/thno.16681