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Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine

Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity. Umbilical cord mesenchymal stem cells (UCMSCs) have powerful regenerative and immunomodulatory potential, and their secreted...

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Detalles Bibliográficos
Autores principales: Monguió-Tortajada, Marta, Roura, Santiago, Gálvez-Montón, Carolina, Pujal, Josep Maria, Aran, Gemma, Sanjurjo, Lucía, Franquesa, Marcel·la, Sarrias, Maria-Rosa, Bayes-Genis, Antoni, Borràs, Francesc E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197063/
https://www.ncbi.nlm.nih.gov/pubmed/28042333
http://dx.doi.org/10.7150/thno.16154