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Targeting of Magnetic Nanoparticle-coated Microbubbles to the Vascular Wall Empowers Site-specific Lentiviral Gene Delivery in vivo

In the field of vascular gene therapy, targeting systems are promising advancements to improve site-specificity of gene delivery. Here, we studied whether incorporation of magnetic nanoparticles (MNP) with different magnetic properties into ultrasound sensitive microbubbles may represent an efficien...

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Detalles Bibliográficos
Autores principales: Heun, Yvonn, Hildebrand, Staffan, Heidsieck, Alexandra, Gleich, Bernhard, Anton, Martina, Pircher, Joachim, Ribeiro, Andrea, Mykhaylyk, Olga, Eberbeck, Dietmar, Wenzel, Daniela, Pfeifer, Alexander, Woernle, Markus, Krötz, Florian, Pohl, Ulrich, Mannell, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197065/
https://www.ncbi.nlm.nih.gov/pubmed/28042335
http://dx.doi.org/10.7150/thno.16192