Cargando…

Inhibition by Multifunctional Magnetic Nanoparticles Loaded with Alpha-Synuclein RNAi Plasmid in a Parkinson's Disease Model

Lewy bodies are considered as the main pathological characteristics of Parkinson's disease (PD). The major component of Lewy bodies is α-synuclein (α-syn). The use of gene therapy that targeting and effectively interfere with the expression of α-syn in neurons has received tremendous attention....

Descripción completa

Detalles Bibliográficos
Autores principales: Niu, Shuiqin, Zhang, Ling-Kun, Zhang, Li, Zhuang, Siyi, Zhan, Xiuyu, Chen, Wu-Ya, Du, Shiwei, Yin, Liang, You, Rong, Li, Chu-Hua, Guan, Yan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197069/
https://www.ncbi.nlm.nih.gov/pubmed/28042339
http://dx.doi.org/10.7150/thno.16562