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Validity Assessment of 5 Day Repeated Forced-Swim Stress to Model Human Depression in Young-Adult C57BL/6J and BALB/cJ Mice
The development of animal models with construct, face, and predictive validity to accurately model human depression has been a major challenge. One proposed rodent model is the 5 d repeated forced swim stress (5d-RFSS) paradigm, which progressively increases floating during individual swim sessions....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Society for Neuroscience
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197406/ https://www.ncbi.nlm.nih.gov/pubmed/28058270 http://dx.doi.org/10.1523/ENEURO.0201-16.2016 |