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Validity Assessment of 5 Day Repeated Forced-Swim Stress to Model Human Depression in Young-Adult C57BL/6J and BALB/cJ Mice

The development of animal models with construct, face, and predictive validity to accurately model human depression has been a major challenge. One proposed rodent model is the 5 d repeated forced swim stress (5d-RFSS) paradigm, which progressively increases floating during individual swim sessions....

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Detalles Bibliográficos
Autores principales: Mul, Joram D., Zheng, Jia, Goodyear, Laurie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197406/
https://www.ncbi.nlm.nih.gov/pubmed/28058270
http://dx.doi.org/10.1523/ENEURO.0201-16.2016