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Repair of DNA Double-Strand Breaks in Heterochromatin

DNA double-strand breaks (DSBs) are among the most damaging lesions in DNA, since, if not identified and repaired, they can lead to insertions, deletions or chromosomal rearrangements. DSBs can be in the form of simple or complex breaks, and may be repaired by one of a number of processes, the natur...

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Detalles Bibliográficos
Autor principal: Watts, Felicity Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197957/
https://www.ncbi.nlm.nih.gov/pubmed/27999260
http://dx.doi.org/10.3390/biom6040047