Analytical Enantio-Separation of Linagliptin in Linagliptin and Metformin HCl Dosage Forms by Applying Two-Level Factorial Design

A novel, stability indicating, reverse phase high-performance liquid chromatography (RP-HPLC) method was developed to determine the S-isomer of linagliptin (LGP) in linagliptin and metformin hydrochloride (MET HCl) tablets (LGP–MET HCl) by implementing design of experiment (DoE), i.e., two-level, fu...

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Detalles Bibliográficos
Autores principales: Jadhav, Sushant B., Mane, Rahul M., Narayanan, Kalyanraman L., Bhosale, Popatrao N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198026/
https://www.ncbi.nlm.nih.gov/pubmed/27763526
http://dx.doi.org/10.3390/scipharm84040671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198026/
https://www.ncbi.nlm.nih.gov/pubmed/27763526
http://dx.doi.org/10.3390/scipharm84040671

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