Effect of Cyclodextrin Types and Co-Solvent on Solubility of a Poorly Water Soluble Drug

The aim of the study was to investigate the solubility of piroxicam (Prx) depending on the inclusion complexation with various cyclodextrins (CDs) and on ethanol as a co-solvent. The phase-solubility method was applied to determine drug solubility in binary and ternary systems. The results showed th...

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Detalles Bibliográficos
Autores principales: Charumanee, Suporn, Okonogi, Siriporn, Sirithunyalug, Jakkapan, Wolschann, Peter, Viernstein, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198028/
https://www.ncbi.nlm.nih.gov/pubmed/27763573
http://dx.doi.org/10.3390/scipharm84040694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198028/
https://www.ncbi.nlm.nih.gov/pubmed/27763573
http://dx.doi.org/10.3390/scipharm84040694

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