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Effect of Cyclodextrin Types and Co-Solvent on Solubility of a Poorly Water Soluble Drug
The aim of the study was to investigate the solubility of piroxicam (Prx) depending on the inclusion complexation with various cyclodextrins (CDs) and on ethanol as a co-solvent. The phase-solubility method was applied to determine drug solubility in binary and ternary systems. The results showed th...
Autores principales: | Charumanee, Suporn, Okonogi, Siriporn, Sirithunyalug, Jakkapan, Wolschann, Peter, Viernstein, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198028/ https://www.ncbi.nlm.nih.gov/pubmed/27763573 http://dx.doi.org/10.3390/scipharm84040694 |
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