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Curcumin as a Modulator of P-Glycoprotein in Cancer: Challenges and Perspectives

Multidrug resistance (MDR) presents a serious challenge to the efficiency of cancer treatment, and may be associated with the overexpression of drug efflux pumps. P-glycoprotein (P-gp) is a drug efflux pump often found overexpressed in cases of acquired MDR. Nevertheless, there are no P-gp inhibitor...

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Detalles Bibliográficos
Autores principales: Lopes-Rodrigues, Vanessa, Sousa, Emília, Vasconcelos, M. Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198046/
https://www.ncbi.nlm.nih.gov/pubmed/27834897
http://dx.doi.org/10.3390/ph9040071