Applications of High-Throughput Sequencing for In Vitro Selection and Characterization of Aptamers

Aptamers are identified through an iterative process of evolutionary selection starting from a random pool containing billions of sequences. Simultaneously to the amplification of high-affinity candidates, the diversity in the pool is exponentially reduced after several rounds of in vitro selection....

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Detalles Bibliográficos
Autores principales: Nguyen Quang, Nam, Perret, Gérald, Ducongé, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198051/
https://www.ncbi.nlm.nih.gov/pubmed/27973417
http://dx.doi.org/10.3390/ph9040076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198051/
https://www.ncbi.nlm.nih.gov/pubmed/27973417
http://dx.doi.org/10.3390/ph9040076

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