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Repeated Long-Term DT Application in the DEREG Mouse Induces a Neutralizing Anti-DT Antibody Response

Regulatory T (Tregs) cells play an important role in mediating tolerance to self-antigens but can also mediate detrimental tolerance to tumours and pathogens in a Foxp3-dependent manner. Genetic tools exploiting the foxp3 locus including bacterial artificial chromosome- (BAC-) transgenic DEpletion o...

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Detalles Bibliográficos
Autores principales: Wang, Junhua, Siffert, Myriam, Spiliotis, Markus, Gottstein, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198145/
https://www.ncbi.nlm.nih.gov/pubmed/28074191
http://dx.doi.org/10.1155/2016/1450398