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Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide

The abnormal fibrillation of human islet amyloid polypeptide (hIAPP) has been implicated in the development of type II diabetes. Aluminum is known to trigger the structural transformation of many amyloid proteins and induce the formation of toxic aggregate species. The (−)-epigallocatechin gallate (...

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Detalles Bibliográficos
Autores principales: Xu, Zhi-Xue, Zhang, Qiang, Ma, Gong-Li, Chen, Cong-Heng, He, Yan-Ming, Xu, Li-Hui, Zhang, Yuan, Zhou, Guang-Rong, Li, Zhen-Hua, Yang, Hong-Jie, Zhou, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198260/
https://www.ncbi.nlm.nih.gov/pubmed/28074190
http://dx.doi.org/10.1155/2016/1867059